TB-500 Dosing Guide:
Protocol, Reconstitution & Tracking

Complete evidence-based TB-500 dosing protocol for 2026. Updated reconstitution steps, injection guidance, and cycle protocols.

⚠️ Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a licensed healthcare provider before starting any peptide or medication protocol.

⚡ TB-500 Quick Reference

Common dose: 2,000–5,000 mcg  |  Frequency: 2x/week loading, weekly maintenance
Half-life: ~4 days  |  Category: Healing & Recovery
Injection sites: Subcutaneous or IM, any site — acts systemically

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What is TB-500?

TB-500 is a synthetic fragment of Thymosin Beta-4, providing systemic healing throughout the entire body from any injection point. Unlike BPC-157's localized effects, TB-500 acts body-wide by promoting cell migration, reducing systemic inflammation, and accelerating tissue repair everywhere. Used for muscle tears, tendon injuries, ligament damage, and post-surgical recovery. Standard protocol: loading phase (2–2.5 mg twice weekly for 4–6 weeks) followed by maintenance (weekly). The DoseIQ app tracks your TB-500 loading and maintenance schedule automatically.

Benefits of TB-500

Dosing Protocols

Below are evidence-based TB-500 dosing protocols for different experience levels and goals. Always start at the lowest effective dose and assess tolerance before increasing.

Loading Phase: 2–2.5 mg twice weekly for 4–6 weeks.
Maintenance: 2–2.5 mg once weekly after loading.
Stack with BPC-157: TB-500 2 mg 2x/week + BPC-157 250 mcg daily.

Reconstitution Guide

Proper reconstitution is critical for accurate dosing. Follow these steps carefully:

1
Add 2 mL BAC water to 5 mg vial = 2,500 mcg/mL
2
2 mg dose = 0.80 mL | 2.5 mg = 1.00 mL
3
Can be mixed with BPC-157 in same syringe
4
Refrigerate; use within 4 weeks

Dosing Reference Table

Use this table to determine your exact injection volume based on vial size and BAC water amount:

Vial SizeBAC WaterConcentrationLow Dose VolHigh Dose Vol
5 mg2 mL2,500 mcg/mL0.80 mL1.00 mL
10 mg2 mL5,000 mcg/mL0.40 mL0.50 mL
5 mg5 mL1,000 mcg/mL2.00 mL2.50 mL

Injection Site Guide

Recommended sites: Subcutaneous or IM, any site — acts systemically

Rotate injection sites to prevent scar tissue buildup. Clean the injection site with an alcohol swab before injecting. Use a 27-29 gauge insulin syringe for subcutaneous injections. Pinch the skin, insert needle at 45-90°, and inject slowly.

Storage Guidelines

Lyophilized (powder) form: Refrigerate at 36–46°F (2–8°C). Protect from light. Most peptides remain stable for 1–2 years unreconstituted.

Reconstituted solution: Refrigerate immediately after mixing. Use within 4 weeks typically. Do not freeze reconstituted peptides — this may damage the peptide structure.

Frequently Asked Questions

Q: What is TB-500 used for?
A: Systemic tissue repair for muscle tears, tendon and ligament injuries, and post-surgical recovery.
Q: What is the loading protocol?
A: 2–2.5 mg twice weekly for 4–6 weeks, then once weekly for maintenance.
Q: Can I stack TB-500 with BPC-157?
A: Yes — classic combo. BPC-157 provides local healing; TB-500 provides systemic effects.
Q: How to reconstitute?
A: 2 mL BAC water + 5 mg vial = 2,500 mcg/mL.
Q: How long until results?
A: Reduced inflammation in 1–2 weeks; structural repair in 4–8 weeks.

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