Semaglutide Dose Calculator
— Free Online Tool

Calculate exact injection volumes, concentrations, and doses per vial for Semaglutide protocols.

⚠️ Medical Disclaimer: This content is for informational purposes only and does not constitute medical advice. Always consult a licensed healthcare provider before starting any peptide or medication protocol.

⚡ Semaglutide Dose Calculator

Concentration—
Volume Per Injection—
Insulin Syringe Units—
Doses Per Vial—

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What is Semaglutide?

Semaglutide is a GLP-1 receptor agonist FDA-approved for type 2 diabetes (Ozempic) and chronic weight management (Wegovy 2.4 mg/week). It works by mimicking GLP-1: increasing glucose-dependent insulin secretion, suppressing glucagon, slowing gastric emptying, and powerfully reducing appetite through brain receptors. Clinical trials showed average weight loss of 15% body weight over 68 weeks. Starting dose: 0.25 mg weekly, titrated every 4 weeks. Compounded semaglutide requires reconstitution with bacteriostatic water. Track your weekly doses and titration schedule with the DoseIQ app.

Semaglutide Quick Reference

ParameterDetails
CategoryGLP-1 / Weight Loss
Common Dose250–2,400 mcg
FrequencyOnce weekly
Half-Life~7 days
Injection SitesSubcutaneous — abdomen, thigh, or upper arm

Benefits of Semaglutide

Common Dosing Protocols

Weeks 1–4: 0.25 mg (250 mcg) weekly — tolerability.
Weeks 5–8: 0.5 mg (500 mcg) weekly.
Therapeutic Range: 1 mg → 1.7 mg → 2.4 mg max, 4 weeks each.

Reconstitution Reference Table

Vial SizeBAC WaterConcentrationLow Dose VolumeHigh Dose Volume
5 mg2 mL2,500 mcg/mL0.10 mL0.40 mL
5 mg1 mL5,000 mcg/mL0.05 mL0.20 mL
10 mg2 mL5,000 mcg/mL0.05 mL0.20 mL

How to Reconstitute Semaglutide

1
Add 2 mL BAC water to 5 mg vial = 2,500 mcg/mL
2
0.25 mg = 0.10 mL | 0.5 mg = 0.20 mL | 1 mg = 0.40 mL | 2 mg = 0.80 mL
3
Inject subcutaneous abdomen, thigh, or upper arm
4
Refrigerate up to 28–56 days

Frequently Asked Questions

Q: What is the starting dose of semaglutide?
A: 0.25 mg (250 mcg) weekly for 4 weeks, then titrate: 0.5 mg → 1 mg → 1.7 mg → 2.4 mg max. Slow titration minimizes nausea.
Q: How do I reconstitute semaglutide?
A: 5 mg vial + 2 mL BAC water = 2,500 mcg/mL. Starting dose 0.25 mg = 0.10 mL on an insulin syringe.
Q: What are the main side effects?
A: Nausea, vomiting, diarrhea (especially during titration). These improve with slow titration. Rare: pancreatitis. Contraindicated with MTC/MEN2 history.

Related Calculators

Tirzepatide Calculator →Ozempic (Semaglutide) Calculator →Wegovy (Semaglutide) Calculator →Liraglutide Calculator →

📱 Track Every Dose with DoseIQ

The #1 peptide tracking app for iPhone. Calculate doses, log injections, set reminders, and track your progress.

⬇️ Download Free on App Store